Researchers from the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology of CAS, and the Shanghai Institute of Immunity and Infection of CAS, found that virus infection-induced immune factor IFN-γ regulates the expansion of dysplastic KRT5⁺ cells through the Yes-associated protein 1 (YAP) axis.

A collaborative team from China discovered that fructose suppresses the polarization of M1-like tumor-associated macrophages (M1-like TAMs), thereby promoting the onset and progression of colorectal cancer. This finding reveals a new functional mechanism of fructose.

Lotus seeds can survive for thousands of years in natural conditions and even germinate under suitable conditions. Understanding the mechanisms underlying lotus seed longevity could provide new strategies for the successful long-term storage of seed crops. Recently, a research team from Wuhan Botanical Garden systematically investigated the components of lotus seeds, specifically the pericarp, cotyledon, and plumule, at physiological, biochemical, and molecular levels, trying to elucidate the inherent mechanisms contributing to their longevity.

Prof. FANG Xianyang from the Institute of Biophysics of the Chinese Academy of Sciences, reviewed three complementary molecular ruler techniques in Current Opinion in Structural Biology on October 22, including electron paramagnetic resonance (EPR), X-ray scattering interference (XSI), and fluorescence resonance energy transfer (FRET).

In a study published in Journal of Environmental Management, researchers from Xishuangbanna Tropical Botanical Garden (XTBG) examined the impacts of rainforest conversion to rubber plantations on soil dissolved organic carbon (DOC), one of the most mobile organic matter (OM) in the terrestrial ecosystem that causes the transformation and migration of carbon, and the ratio of carbon and nitrogen (C:N).

Recently, Prof. ZHAO Fangqing’s team from the Institute of Zoology of the Chinese Academy of Sciences, has developed a novel targeted RNA sequencing approach called PROgrammable Full-length Isoform Transcriptome sequencing (PROFIT-seq). This strategy effectively captures a broad spectrum of transcriptome samples, providing effective enrichment of target transcripts while maintaining unbiased quantification of the entire transcriptome.

In a study published in BMC Plant Biology, researchers from Xishuangbanna Tropical Botanical Garden compared competitive outcomes between invasive C. odorata and two native plants under different phosphorus and irradiance levels to provide valuable information for understanding the invasion mechanism of C. odorata.

A research group from Tianjin Institute of Industrial Biotechnology of the Chinese Academy of Sciences, along with collaborators, revealed the actual function of EfpA as a lipid transporter and uncovered the structural basis for its interaction either with both phosphatidic acid and the drug molecule, a BRD-8000.3, which will facilitate the development of anti-TB drugs.

A team led by Prof. CHENG Hong from the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences, collaborating with Prof. ZHOU Yu from Wuhan University, proposed a novel "degradation-centric" model of RNA sorting, challenging the prevailing view of "export-centric."

A research group led by Prof. CAO Te from the Institute of Hydrobiology of the Chinese Academy of Sciences demonstrated that benthic fish may exert diametrically opposed effects on water quality in the presence and absence of submerged macrophytes.

Cold damage is a major challenge in rice production, and identifying key gene modules in signaling pathways is a crucial means of addressing this issue. A Chinese research team has recently discovered a part of the plant’s cell membrane that helps plants sense when it's cold.

Perennial ryegrass (Lolium perenne L.), widely cultivated in cool-season for forage supply and turfgrass, is extremely susceptible to high temperature. A recent study has discovered a pivotal stress-responsive gene, combating heat stress in perennial ryegrass.