A research team led by Prof. REN Peigen from the Shenzhen Institute of Advanced Technology of Chinese Academy of Sciences, along with the collaborators, discovered that the well-known bone matrix protein Osteocalcin (OCN) can regulate chondrocyte differentiation and endochondral ossification, which provides new information to explain the complicated and ambiguous role of osteocalcin in bone turnover.

A research team led by LIU Ji from the University of Science and Technology of China of the Chinese Academy of Sciences revealed an adrenal independent pathway, hypothalamus-sympathetic-liver (HSL) axis, to mediate stress-induced glucose release.

Prof. WANG Qian's team from the University of Science and Technology of China of the Chinese Academy of Sciences and Prof. BAI Fang from ShanghaiTech University proposed a deep learning model for predicting protein conformational changes, representing a step forward in the predictive modeling of protein dynamics.

A collaborative team from the Institute of Biophysics of the Chinese Academy of Sciences and Beijing Normal University recently revealed that macaques, like humans, also hold knowledge about object colors, after functional MRI (fMRI) and behavioral eye-tracking experiments in macaques.

Researchers from the Shenzhen Institute of Advanced Technology, and the collaborators, demonstrated a new model of early evolution in the transition of tumors from polyclonal to monoclonal, and elucidated the mechanisms of intercellular communication and the interaction underlying the polyclonal origin of tumors.

A research group led by Prof. CAI Xinxia from the Aerospace Information Research Institute of the Chinese Academy of Sciences developed a novel drug-loaded hydrogel-coated microelectrode array (MEA), which allows for long-term, high-quality detection of neural activity.

A research team led by Dr. CHENG Wenxiang from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, along with the collaborators, discovered that overexpression of Angiopoietin-like protein 4 (ANGPTL4) is a characteristic of RA patients, and that neutralizing the C-terminal fragments of ANGPTL4 reduces the severity of arthritis in animal models.

A team of scientists from the Chinese Academy of Sciences (CAS) and BGI Research has uncovered the intricate mechanisms by which immunoglobulins influence the aging process, a finding that might reshape our understanding of aging. This research, published in Cell on Nov. 4, not only charts a high-precision map of aging across various organs but also reveals the dual-edged sword of immunoglobulins in systemic aging.

A group of researchers from Xishuangbanna Tropical Botanical Garden (XTBG) recently investigated the accumulation of polystyrene nanoplastics (PS-NPs) in leafy vegetable leaves and its ecological consequences. They also explored the impact of PS-NPs on plant leaf cuticles and trichomes, and analyzed the potential ecological effects.

“How is plant growth controlled?” and “What is the basis of variation in stress tolerance in plants?” were among the 125 most challenging scientific questions, according to the journal Science in 2016. Strigolactone (SL) is an important plant hormone that plays essential roles in regulating branch number, a key growth and development trait for plants. Recently, scientists from the Chinese Academy of Sciences (CAS) have uncovered the mechanism behind SL perception and its key role in the tillering response to nitrogen.

Recently, a collaboration between the Institute of Biophysics and the National Institute of Biological Sciences led to the discovery of a novel killer gene, tdk1, in the fission yeast (Schizosaccharomyces pombe). This research revealed the molecular and structural mechanisms by which its protein product TDK1 controls cell survival.

A group of researchers led by Dr. HE Kangmin from the Institute of Genetics and Developmental Biology and Dr. FANG Xiaohong from Hangzhou Institute of Medicine, has identified focal adhesions as the subcellular signaling hubs organizing the activation of PI3K-PI(3,4,5)P3-AKT signaling in mammalian cells under basal conditions.