A team led by WU Beili from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences, along with the collaborators, determined the structures of GPR1 bound to chemerin and β-arrestin 1 or β-arrestin 2, as well as the structure of GPR1– β-arrestin 1 complex in the absence of chemerin. They elucidated a picture of arrestin-mediated modulations of GPR1.
A joint research team from the Institute of Biophysics and Tsinghua University has developed a novel live-cell DNA imaging technology called CRISPR PRO-LiveFISH (Pooled gRNAs with Orthogonal bases LiveFISH), a novel live-cell DNA imaging technology that integrates CRISPR technology with expanded genetic alphabet technology.
A research team led by Profs. XU Tao and HE Shunmin from the Institute of Biophysics of the Chinese Academy of Sciences conducted a comprehensive analysis of mitochondrial variants and nuclear mitochondrial DNA segments from 7,331 individuals by integrating the NyuWa Genome Resource with data from the 1000 Genomes Project.
A research team led by Prof. LI Hongchang from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences uncovered a fundamental plasma membrane remodeling mechanism that governs the mitotic cell rounding.
A new study of gibbons has resolved key debates about their evolutionary history, providing critical insights for conservation efforts and presenting extensive genomic resources. These include chromosome-level reference genomes for all four genera, as well as whole-genome resequencing of 18 extant species.
A new study led by Prof. WANG Guodong from the Kunming Institute of Zoology provides insights into the parallel migration patterns of dogs and humans across Eastern Eurasia during the Holocene. By analyzing 73 ancient dog genomes, including 17 newly sequenced samples, researchers found that shifts in canine ancestry tracked major human migrations over the past 10,000 years.
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