Dec 23, 2025
Cognitive Inflexibility Is a Shared Phenotype for Patients with Schizophrenia and Obsessive-compulsive Disorder
Researchers led by Dr. Raymond Chan from the Institute of Psychology have examined patients with co-morbidity of schizophrenia and obsessive-compulsive disorder, a condition known as "schizo-obsession", and showed that there were specific superimposed neural effects of combined schizophrenia and obsessive-compulsive symptoms at both white matter connectivity and resting-state functional connectivity, compared to patients with either schizophrenia or obsessive-compulsive disorders, as well as healthy controls.
Behavioral Biology;Cognitive Research;Health