A recent study by researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, has uncovered a crucial mechanism in cellular material management: endosome maturation. This process is essential for maintaining cell health and functionality by enabling the sorting, transport, and degradation of materials within cells. It plays a key role in nutrient absorption, immune defense, signal transmission, and waste recycling.

A research group led by Prof. FU Xiongfei at the Shenzhen Institute of Advanced Technology has developed a synthetic host-virus co-propagation system, which demonstrates that chemotaxis-mediated range expansion can contribute to the suppression of infectious disease, independently of intricate host-virus dynamics and specific environmental conditions.

A research team led by Prof. ZHENG Mingyue from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences introduced a new deep learning method, SurfDock, which demonstrates good performance in both retrospective and prospective virtual screening tasks.

A research team led by Profs. XU Tao and HE Shunmin from the Institute of Biophysics of the Chinese Academy of Sciences has recently constructed a global polymorphism genetic map of variable number tandem repeats (VNTRs), termed the NyuWa VNTR Polymorphism Map.

Researchers from Xishuangbannna Tropical Botanical Garden of the Chinese Academy of Sciences and the University of California, San Diego, showed that fear responses of honeybees to predators are mediated by dopamine, and these responses not only increase the alertness of honeybees but also affect their cognitive abilities.

A research team led by Prof. ZHAO Xiaoli from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, and collaborators, reported a smartphone-controlled programmable handheld printer for in situ skin wounds dressing.

Researchers from Xishuangbanna Tropical Botanical Garden of the Chinese Academy of Sciences, using tree-ring width data of Pinus latteri from three sites in southern Laos, developed a regional composite chronology and reconstructed the hydroclimatic variability during 1885–2019.

Dr. TIAN Ye's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, identified eight genera of bacterial isolates from Arabidopsis root bacterial isolates that could extend lifespan in C. elegans, and found that Mycobacterium sp. Root265 displayed the most pronounced extension effect.

Chinese scientists have developed a novel two-dimensional (2D) framework, the “Health State Map (HSM),” to define metabolic health and nutritional capacity. The study was published online in National Science Review.

A team led by Prof. LU Xiaojie and Prof. XU Yechun from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences introduced a novel covalent DNA-encoded library (DEL) workflow which enables covalent screening against cysteine-rich non-structural proteins of SARS-CoV-2, leading to the identification of covalent hit compounds with novel scaffolds and allosteric binding modes.

A research team from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences revealed that aging specifically impairs the generation of CD8⁺ tissue resident memory T cells (TRM) and thus compromises the antitumor defensive activity of aged CD8⁺ T cells.

A Chinese research team has recently traced the discovery of itaconate as an immune modulator and effector molecule, described the development of fluorescent probes for itaconate, and summarized recent research findings on the mechanisms of itaconate transport between cells in a review article published in Cell Insight​ on Nov. 22.