DNA Methylation Subtypes Guiding Prognostic Assessment and Linking to Responses DNA Methyltransferase Inhibitor SGI-110 in Urothelial Carcinoma
Scientists from the Beijing Institute of Genomics of the Chinese Academy of Sciences and Department of Urology, Peking University First Hospital, reported the epigenomic features and profiles of UTUC and UCB, identified DNA methylation subtypes with potential risk stratification of tumors, and evaluated therapeutic efficacy and targets of the DNA methyltransferase inhibitor SGI-110.
Jul 22, 2022