Researchers from LI Jiayang's group at the Institute of Genetics and Developmental Biology provided an effective strategy to overcome the bottleneck of rice yield using the tiling deletion to edit the cis-regulatory region of rice pleiotropic gene IPA1 and breaking the tradeoff of rice yield component traits.

MIAO Peng's group from the Suzhou Institute of Biomedical Engineering and Technology (SIBET) has recently developed an electrochemical DNA nanomachine based on looped bipedal DNA walking reaction for highly sensitive analysis of nucleic acids.

In a recent study, researchers from the Xishuangbanna Tropical Botanical Garden have assessed the conspecific aggressiveness plasticity in response to the social environment (social living, isolation and resocialization) of Toxeus magnus. They further examined the proximate mechanism underlying the reversal to low aggression during resocialization.

The researchers reported the cellular origins of cardiac macrophages in the developing heart, by using a series of lineage tracing systems, which provide new insights into cardiac development, pathogenesis and regeneration.

A team led by WU Beili and ZHAO Qiang of the Shanghai Institute of Materia Medica, in collaboration with a group led by SHUI Wenqing of ShanghaiTech University, made a breakthrough in the field of orphan receptors by determining four cryo-electron microscopy (cryo-EM) structures of two adhesion receptors, ADGRD1 and ADGRF1, in complex with G proteins and by carrying out extensive functional studies.

Recently, researchers from Guangzhou Institutes of Biomedicine and Health and the Second Affiliated Hospital of Zhejiang University School of Medicine have revealed the mechanisms of FNZ inducing parkinsonism by provoking the integration of mitochondria and lysosomes, named as mitolysosome, and causing mitochondrial reduction in brains.

Dr. JI Hongbin's team from the Center for Excellence in Molecular Cell Science, reported that chemotherapy-resistant small cell lung cancer (SCLC) has undergone metabolic reprogramming and become addicted to the mevalonate (MVA)-geranylgeranyl diphosphate (GGPP) pathway, and statin might serve as a potential effective drug for overcoming chemotherapy-resistance in SCLC in clinic.

A research team from the Shenzhen Institute of Advanced Technology suggested that the functional disruption of the cerebrovascular system could be more significant in the disease characterization of glioma.

In a recent study, researchers from the Xishuangbanna Tropical Botanical Garden (XTBG) tried to estimate the potential response of soil aggregates of different particle sizes to splash erosion under natural rainfall conditions by comparing two land-use regimes, primary tropical rainforest and managed rubber plantation in Xishuangbanna.

Recently, researchers from the Suzhou Institute of Biomedical Engineering and Technology and South China University of Technology collaborated to develop a near-infrared (NIR)-driven nanoassemblies with size and charge dual transformation for the combination of photocontrolled chemotherapy and immunotherapy in breast cancer.

Research teams led by Prof. PAN Guangjin and Prof. LAI Liangxue from the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences made new progress on hPSCs interspecies chimerism. They developed an enhanced hPSCs in interspecies chimerism that allows to obtain functional human blood cells through interspecies chimerism technology for the first time.

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology and Peking Union Medical College Hospital have developed an automated system that provides swift, accurate results for determining the best antibiotics at the right dose.