Main functions: to draw up schemes of hi-tech industry development for the CAS; to supervise profits from CAS investments on the basis of property rights; and manage State-owned assets in CAS-run business entities. The Bureau of Domestic Cooperation serves as a liaison organ for integrating research institutes with local enterprises, administers technology transfers and hi-tech industrialization, and keeps in constant contact with CAS institutes engaged in technological development.

Divisions: Division of Comprehensive Planning, Division of Northeast China, Beijing and Tianjin Affairs, Division of East China Affairs, Division of Central and South China Affairs, Division of West China Affairs, and Office of CAS Scientists Working as Local Administrative Officials.